Antimicrobial, Proximate, and Toxicity Studies of the Aerial Plant Parts of Drynaria Laurentii obtained from Effurun Delta State

Abstract

Phytochemical screening revealed the presence of Saponin, tannins, phenolic compound, carbohydrates, glycoside, flavonoid, alkaloids, protein, and steroids for the solvents extracts. Proximate analysis results recorded 17.40, 7.4, 4.31, 6.02, 54.16, and 9.81 against moisture content, ash, fat, crude fiber, carbohydrate, and crude protein respectively. Mueller Hinton agar medium with some clinical pathogenic microbes such as Methicillin Resist Staphaureus, Staphylococcus aureus, Vancomycin-Resistant enterococci, Helicobacter pylori, Escherichia coli, Klebsiella pneumoniea, Salmonella typhi, Proteus mirabilis, Candida albicans, Candida krusei, Candida tropicalis revealed that the minimum inhibitory concentration for all the solvent extracts and organisms occurred at 2.5 mg/ml, except for Salmonella typhi which occurred at 5 mg/ml in methanol extract. Minimum bacterial/fungicidal concentration for all organisms occurred at 10 mg/ml except for Methicillin Resist Staphaureus, Escherichia coli, and Candida tropicalis occurred at 5 mg/ml in ethyl acetate and Helicobacter pylori which occurred at 5 mg/ml in methanol. The aqueous plant extract was not toxic at 1 mg/l, 10 mg/l, and 100 mg/l indicating the safety of the plant as a good source of medicinal plant. Generally, Drynaria laurentii possesses bioactive phytochemicals with an appreciable level of nutrient contents in the dry samples; inhibit the growth of microorganisms and not toxicity at the stated concentrations.